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Psychoactive Properties of Ingesting Cannabis VS Smoking

Updated: Nov 2, 2022

Medical decisions should not be made based on advertising. Consult a physician on the benefits and risks of particular medical marijuana products.


  • THC is the primary psychoactive compound present in the cannabis plant that possesses psychoactive properties.

  • The nature, length, and effect of THC differ for both smoking and ingestion.

  • Smoking produces more pronounced effects as it directly enters the bloodstream through the respiratory pathway. The edibles/ ingested cannabis takes time for the desired action.

  • Ingestion prevents the direct contact of smoke generated by smoking and is much safer.

  • Coco Dispensaries has a vast menu that contains the desired beneficial cannabis products you need to check out.


Modes of Cannabis Consumption

Cannabis intake have different ways, but today the following are entitled to be discussed.

A raw plant isn't proactive because the compound THC gets active when it is allowed to heat.

The non-active THCA decarboxylate in the plant converts into THC.


Smoking cannabis involves the burning and inhaling of vaporized cannabinoids ("smoke") from various modules.

Ingesting Cannabis/Edibles

Cannabis as Edibles occurs in foods, including butter and bakery products.

In certain countries, you may find cannabis infused in a beverage, bhang.

Common Forms of Edibles

You can find edibles as:

  • Baked products (Waffles, cookies, and brownies)

  • Beverages (Coffee, energy drinks, iced tea, alcohol, tea, and soda)

  • Sweets (Gummies, lollipops, marshmallows, lozenges, chocolate, and chewing gums)

THC (delta-9-tetrahydrocannabinol)

THC is the primary psychoactive compound present in the cannabis plant that possesses psychoactive properties. How does THC produce psychoactive action?

Cannabis Intake (smoking, edibles)

After smoking or ingestion, the active compound THC reaches the mainstream (blood). The time required is variable because of the different routes of administration. THC enters CNS through blood.

Interaction with CB1 Receptor

It gets attached to its receptor for producing the desired psychoactive action. THC behaves similar to the endogenous cannabinoids and binds to the cannabinoid CB1 receptors on presynaptic nerve terminals in the CNS.

Release of Neurotransmitters

As a result of binding, excitatory and inhibitory neurotransmitters start to release in the brain. It results in the inhibition of the adenylate cyclase enzyme and several channels.

Interaction with MAP kinase

After that, THC binding to CB1 receptors activates the MAP kinase pathway that produces ecstatic feelings.

Psychoactive Action

All the above channels and pathways produce psychoactive properties, making the individual alert and active, fleeing joy (Dopamine release).